your thoughts on st. john's wort, please...

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Have you ever taken it for long periods? Did it work? I tried the Holland and Barrett stuff for a while, but it just gave me stomach ache. The stuff I'm taking now seems better. But sometimes when you mention it to people they look at you oddly, cross themselves and back away with their handbags over their noses. Have you tried it? Any experiences to report, good or bad?

hobart paving (hobart paving), Wednesday, 23 February 2005 10:39 (twenty years ago)

It's fucking ace in high doses. I tried snorting it once too, but that was a terrible terrible mistake.

alix (alix), Wednesday, 23 February 2005 10:45 (twenty years ago)

Almost tried it but was advised not to while on prescribed AD's. I may give it a go, but only if I can be absolutely guaranteed I'll feel different.

Rumpy Pumpkin, Wednesday, 23 February 2005 11:05 (twenty years ago)

It's wack. Benzos are forever, oh God I love clonazepam. So gently I live.

LeCoq (LeCoq), Wednesday, 23 February 2005 11:10 (twenty years ago)

I've been taking it since September and have seen my depression gradually clear up (not totally, but there's a marked improvement). However, I've also been using a daylight simulator and I suspect that's made more of a difference. Until I try using one but not the other I won't know for sure, but I'm not going to take any risks for the sake of proving things by science. They sell huge bottles of SJW very cheap in Savers. Holland & Barrett is a total rip off.

Madchen (Madchen), Wednesday, 23 February 2005 11:12 (twenty years ago)

What is a daylight simulator, one of those big lamp things??

I've bought the liquid rather than the tablets. It was quite expensive, but it seems to work. The only thing is it makes me go really, really dopey. I keep having "blank" periods.

hobart paving (hobart paving), Wednesday, 23 February 2005 11:18 (twenty years ago)

I found it didn't work at all for me. Made no difference whatsoever. But my friend found it helped her, so I guess you don't know until you try it, it might work for you.

Colonel Poo (Colonel Poo), Wednesday, 23 February 2005 11:27 (twenty years ago)

How can you bear the taste of the liquid version? It's revolting. I've got two bottles of it, and I'm going to have to throw it away.

I've never suffered from depression but I do occasionally get premenstrually grumpy, and taking St John's Wort for a day or two really makes a difference to that and returns me to my usual sunny self. It's ace.

C J (C J), Wednesday, 23 February 2005 11:34 (twenty years ago)

Ew, liquid? My tablets taste pretty rank (cheap tablets = no coating) but I really wouldn't want to drink the stuff.

Yeah, it's a lamp - I got it from Outside In

Madchen (Madchen), Wednesday, 23 February 2005 11:37 (twenty years ago)

You can get it in tea form as well which is presumably fairly weak but might make you less dopey?

Archel (Archel), Wednesday, 23 February 2005 11:38 (twenty years ago)

NB it interferes with oral contraceptives, and getting pregnant when you weren't planning to would be really depressing, no?

Liz :x (Liz :x), Wednesday, 23 February 2005 11:42 (twenty years ago)

Yes, this is why I don't take it. Don't think hp needs to worry on that score though...?

Archel (Archel), Wednesday, 23 February 2005 11:43 (twenty years ago)

NB it interferes with oral contraceptives, and getting pregnant when you weren't planning to would be really depressing, no?

It would certainly be rather surprising.

hobart paving (hobart paving), Wednesday, 23 February 2005 11:47 (twenty years ago)

I'm sure it would, Ian.

Liz :x (Liz :x), Wednesday, 23 February 2005 11:47 (twenty years ago)

Yeah, it's a lamp - I got it from Outside In

Hmm..I've seen these before. They seem very expensive, though. Is it very lovely??

hobart paving (hobart paving), Wednesday, 23 February 2005 11:48 (twenty years ago)

I tried it back in 1999 or 2000. I wasn't depressed - I just wanted to see if it gave an improved quality of life. I'm attracted to the idea of legal and harmless chemical bliss.

It didn't do anything for me.

Bob Six (bobbysix), Wednesday, 23 February 2005 11:50 (twenty years ago)

How can you bear the taste of the liquid version? It's revolting. I've got two bottles of it, and I'm going to have to throw it away.

Mine just tastes of alcohol. That doesn't bother me unduly, although its a little weird before my Weetabix. It tastes a hell of a lot better than the Vitamin B tablet I have to neck with it.

hobart paving (hobart paving), Wednesday, 23 February 2005 11:50 (twenty years ago)

i used it for a while when i lived in chicago, and it worked for me (although i also started exercising regularly as well, which very possibly made as much if not more of a difference)

didn't need to stay on it long term, and wouldn't because of the messing up the pill thing, anyway.

colette (a2lette), Wednesday, 23 February 2005 11:50 (twenty years ago)

I am interesting in finding out how it interferes with the pill, as my reasons for being on the pill are not primarily for birth control and I would quite like to start taking SJW again, but don't want to fuck up what the pill is actually useful for. It's all a bit complicated.

alix (alix), Wednesday, 23 February 2005 11:51 (twenty years ago)

You can get it in tea form as well which is presumably fairly weak but might make you less dopey?

Hmm...yes...I hadn't thought about that, and will investigate. Thanks, oh wise Archel.

hobart paving (hobart paving), Wednesday, 23 February 2005 11:51 (twenty years ago)

Is Savers a Scottish thing? I like cheap. I haven't seen any in Peckham and Peckham is the birth place of cheap. Aah Lidl AND Netto, both within walking distance.

alix (alix), Wednesday, 23 February 2005 12:02 (twenty years ago)

Savers is the cheap Superdrug. They are one of my new customers. As yet I don't have a database of store locations but I can confirm that there is one in Thetford. (Wherever that is).

Rumpy Pumpkin, Wednesday, 23 February 2005 12:31 (twenty years ago)

Thetford is in Norfolk. I have spoken to some of its residents this very morning.

alix (alix), Wednesday, 23 February 2005 12:39 (twenty years ago)

you'd need something stronger than some pissy flower remedy if you live in thetford.

stelfox, Wednesday, 23 February 2005 12:44 (twenty years ago)

Holy crap! My mum bought me 200 capsules of this last week. Prescient or what? I won't be able to fully comment for about a month and between the life-stress and the deaths of 2 friends lately, it's hard to give 'em much props.

Deerninja B4rim4, Plus-Tech Whizz Kid (Barima), Wednesday, 23 February 2005 13:15 (twenty years ago)

SJW speeds the metabolism of the liver with various substances, hence its interference with the pill. and very possibly any other prescription drugs/vitamins that you're taking. there's a chance that under the influence of SJW the liver will just clean out your BC before it has time to have its intended effects.

JuliaA (j_bdules), Wednesday, 23 February 2005 14:39 (twenty years ago)

I see. So all effects of the pill would be messed with. Guess I'll just have to find other ways of being perky.

alix (alix), Wednesday, 23 February 2005 14:43 (twenty years ago)

if you're using BC for reasons other than birth control, then it doesn't seem that it would hurt to try it and see...it probably depends on the specific effects of your drug and how quick they are, your individual liver metabolism, etc etc. if it messes with things, you can always go off it, since IIRC it has a fairly short half-life and thus won't be sticking around in your system for very long. it's just a risk you take with that particular supplement, and obv if you're looking not to get pregnant, it's a big risk.

JuliaA (j_bdules), Wednesday, 23 February 2005 14:59 (twenty years ago)

I'm just here to second the clonazepam endorsement.

sugarpants (sugarpants), Wednesday, 23 February 2005 15:19 (twenty years ago)

what does clonazepam help with for you? i just take it to sleep, and it doesn't seem to do anything else...

JuliaA (j_bdules), Wednesday, 23 February 2005 15:20 (twenty years ago)

Well, it does help me sleep, but it also helps with anxiety/agoraphobia issues without making me feel completely zonked. It's also cheap as hell on my insurance plan.

Basically, it helps me dislike strangers less — at least until weed is less, uh, illegal.

sugarpants (sugarpants), Wednesday, 23 February 2005 15:57 (twenty years ago)

it made me grind my teeth and gave me that jumping legs thing.

jed_ (jed), Wednesday, 23 February 2005 16:00 (twenty years ago)

SJW speeds the metabolism of the liver with various substances, hence its interference with the pill. and very possibly any other prescription drugs/vitamins that you're taking. there's a chance that under the influence of SJW the liver will just clean out your BC before it has time to have its intended effects.

-- JuliaA (j(underscore)bdule...), February 23rd, 2005.

Wow, an anti-depressant that cleans out your liver ... That's two problems solved!

fields of salmon (fieldsofsalmon), Thursday, 24 February 2005 07:37 (twenty years ago)

this info isn't entirely accurate but I figure I might as well pass it along

"There was a report in New Scientist recently which stated that the photosensitive properties of the hypericin in St John's Wort could promote cataracts in rats. There are no reports of the same occurring in humans.

Recommendation As a precaution, the researchers recommend that if you are in the sunshine, you should wearing 'UV-resistant' wrap-around sunglasses, if you are taking St John's Wort. Sunlight shining on the eyes is a cause of cataract in any case, so this is good advice to follow whether or not you are taking St John's Wort."

Sébastien Chikara (Sébastien Chikara), Thursday, 24 February 2005 14:53 (twenty years ago)

I was depressed most of college, and when I got out, winding up in my parents' basement, I figured something had to give or I'd just get worse. On a lark I tried the stuff out and it completely changed my disposition. At graduation I was grumpy, moody, anti-social, and completely pessimistic; by the end of the summer I go stretches when I felt alright lasting longer than anytime since I was a kid. I still use it x years later. So anyways, long story short, I totally recommend it, with the caveat that my dramatic change might coincide with finishing up one phase of life and commencing another.

logged out, Thursday, 24 February 2005 15:04 (twenty years ago)

Have any of you that have tried it found that taking it makes you tired? I'm wondering if it just doesn't suit me. It suits my mood fine, but the constant walking into walls and forgetting what I'm saying in the middle of a sentence is starting to get a bit old.

hobart paving (hobart paving), Friday, 25 February 2005 12:21 (twenty years ago)

My ex-boss bought me some SJW pills to help improve my memory. There was no discernible change to me in any way other than my burps smelled of the foul-tasting and enormous pills. Ew.

Markelby (Mark C), Friday, 25 February 2005 12:52 (twenty years ago)

Just spring for the Fluoxetine, it's cheap and it really works (this all natural business is a bunch of horseshit)

Carl Jo Wheepers, Friday, 25 February 2005 12:55 (twenty years ago)

Just spring for the Fluoxetine, it's cheap and it really works (this all natural business is a bunch of horseshit)

Eek no... it might work for you, but my experience of anti-depressants fell somewhat short of a life full of ecstatic joy. Quite a long way short, actually. I'll spare you the details.

hobart paving (hobart paving), Friday, 25 February 2005 13:03 (twenty years ago)

Worked for me too. I found it worked like a safety net, when I felt down I was just a little further off the bottom than before and bounced back more quickly. It also had some positive effects on anxiety and confidence and I credit it with getting me out of a dead end job.

It's not something you can just pop though, take it for at least a couple of months before you decide it's not working for you.

After 2 or 3 spells of long-term use (6-9 months) I found I didn't need it anymore, I think my brain just reshaped itself to deal with things better.

holojames (holojames), Friday, 25 February 2005 20:13 (twenty years ago)

four years pass...

i'm so skeptical of things like this

Surmounter, Wednesday, 25 February 2009 16:03 (sixteen years ago)

http://news.bbc.co.uk/2/hi/health/1917359.stm

The popular herbal supplement, St John's wort, is an ineffective treatment for depression, a major study has found.

The use of herb has grown massively in recent years as more people opt for so-called natural medicines.

Researchers have conducted the largest ever clinical trial into the impact of the herb on major depression - a moderately severe form of the condition.

The researchers, from Duke University Medical Center in North Carolina, found it had no more impact than a dummy medicine.

Dr Jonathan Davidson, director of the Anxiety and Traumatic Stress Program at Duke, said: "Major depression is treatable. But this research suggests that major depression of at least moderate severity should not be treated with St. John's wort.

it's darn and ielle is hot (and what), Wednesday, 25 February 2009 16:09 (sixteen years ago)

I took it briefly a decade ago while going through issues, and not only did it not help, but I felt numbness in the tips of my fingertips and toes. The numbness went away when I stopped taking it.

System Jr. (Mackro Mackro), Wednesday, 25 February 2009 16:59 (sixteen years ago)

i suffer from excessive feeling in my fingers and toes. is st. john's wort right for me?

andrew m., Wednesday, 25 February 2009 17:02 (sixteen years ago)

st. john's wort is only right for people who think that wort is a delicious snack. otherwise, no.

System Jr. (Mackro Mackro), Wednesday, 25 February 2009 17:23 (sixteen years ago)

i am the large internet doctor

System Jr. (Mackro Mackro), Wednesday, 25 February 2009 17:23 (sixteen years ago)

i tried it for a little bit back when i was debating getting some help. i soon realized that i needed some actual medicine.

andrew m., Wednesday, 25 February 2009 17:45 (sixteen years ago)

"a dummy medicine." thank you BBC. because "placebo" is one of those difficult words.

They don’t understand. And I eat a lot of matzo brie. (contenderizer), Wednesday, 25 February 2009 17:47 (sixteen years ago)

meds

System Jr. (Mackro Mackro), Wednesday, 25 February 2009 17:55 (sixteen years ago)

seven months pass...

just started this today cause i really hate how the "real" stuff turns my sine wave moods into a flat line and i don't want back to that again

BIG HOOS aka the steendriver, Monday, 5 October 2009 19:17 (sixteen years ago)

you might want to investigate 5HTP, hoos?

personally st johns wort never did anything, although it did make middle-aged women in health food and herbal supplement shops cluck at me concernedly

thomp, Monday, 5 October 2009 19:19 (sixteen years ago)

5HTP?

BIG HOOS aka the steendriver, Monday, 5 October 2009 19:20 (sixteen years ago)

http://en.wikipedia.org/wiki/5-Hydroxytryptophan

available in a similar set of places to st john's wort. it's a chemical precursor to seratonin; the wiki link goes into more detail about the action of it and the enzyme that breaks it down, etc.

personally and anecdotally i've found it effective; the last big study said it probably is but there's not been enough research to say for certain

thomp, Monday, 5 October 2009 19:24 (sixteen years ago)

St. John's says it's a "mood enhancer" on the label & that's how it worked for me when I tried it. It just turned all my emotions up to 11.

existential eggs (Abbott), Monday, 5 October 2009 19:40 (sixteen years ago)

That meant irritation and ennui became rage and woe.

existential eggs (Abbott), Monday, 5 October 2009 19:41 (sixteen years ago)

Major depression probably is a diagnostic category into which several different syndromes, with similar symptoms, are swept. I suspect SSRIs and serotonin are only one of them. If St. John's Wort works for you with few side effects, bully.

St. John's Wort didn't work for me. Prozac worked a little. Zoloft worked well, but has a short half-life so I could feel the blues after missing a single dose. Right now, 5-HTP & DHA (from fish oil), plus prescribed Zoloft, is keeping me out of bed and active. Perhaps part of my coctail is unneccessary. I'm not risking it.

St. Matthew reindeer (Derelict), Monday, 5 October 2009 20:03 (sixteen years ago)

should read: "SSRI treatable low-synaptic serotonin" above

St. Matthew reindeer (Derelict), Monday, 5 October 2009 20:05 (sixteen years ago)


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