Most anything by Native Instruments - esp. Absynth & Reaktor (softsynths)
Propellerheads Reason for a preconfigured dance production environment.
Max/MSP for the technically inclined. Most flexible software for music creation/manipulation, but worst learning curve.
Protools or Spark for pro-quality mastering.
Cubase or Logic for a powerful MIDI+Audio sequencing set-up.
None of these are free, but there is a free version of Protools that is quite handy..
― pete from the street, Thursday, 9 October 2003 16:31 (twenty-two years ago)